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Metabolism & incretins

SLU-PP-332

Also known as: ERR-Agonist, Exercise Mimetic

A potent, selective agonist of the oestrogen-related receptors ERRα and ERRγ, studied as an "exercise mimetic" in endurance and metabolism research.

Structure

Sequence
Nicht-peptidisch (Small Molecule)
Molecular formula
C₂₉H₂₄F₃NO₄
Molecular weight
515.50 Da
Amino acids
n/a (not a peptide)

Mechanism of action

SLU-PP-332 activates ERRα and ERRγ, nuclear receptors that govern oxidative metabolism and muscle fibre type. In animal models this raises the expression of genes for mitochondrial biogenesis and fatty acid oxidation.

Studies

More in Metabolism & incretins

More detail (research areas, comparisons, FAQ): German lexicon entry.