Growth hormone axis
Hexarelin
Also known as: Examorelin, HEX, EP-23905
A synthetic hexapeptide growth hormone secretagogue with one of the strongest growth hormone releasing effects in its class. Hexarelin is also studied for cardioprotective properties.
Structure
- Sequence
- His-D-2-MeTrp-Ala-Trp-D-Phe-Lys-NH₂
- Molecular formula
- C₄₇H₅₈N₁₂O₆
- Molecular weight
- 887 Da
- Amino acids
- 6
- Half-life
- ~70 minutes
Mechanism of action
Hexarelin activates the ghrelin receptor in the pituitary and stimulates strong growth hormone release. It also binds CD36 receptors in heart tissue, where it has growth hormone-independent effects.
Studies
More in Growth hormone axis
More detail (research areas, comparisons, FAQ): German lexicon entry.