Skin & copper peptides
KPV
Also known as: Alpha-MSH (11-13), Tripeptid
A tripeptide made of the last three amino acids of alpha-melanocyte-stimulating hormone (α-MSH). KPV has anti-inflammatory properties without the pigmenting effects of the full hormone.
Structure
- Sequence
- Lys-Pro-Val
- Molecular formula
- C₁₆H₃₀N₄O₄
- Molecular weight
- 342.4 Da
- Amino acids
- 3
Mechanism of action
KPV inhibits activation of the NF-κB pathway, a central regulator of inflammation. In cell models it enters the nucleus and suppresses the transcription of pro-inflammatory genes.
Studies
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More detail (research areas, comparisons, FAQ): German lexicon entry.